logo
Call Us+65‎ 6908‎ 9705
contact us

Liquid PDO Thread Lift in Singapore

For patients seeking skin rejuvenation without surgery, the Liquid PDO Thread Lift is a clinically grounded approach to improving skin firmness, elasticity, and facial contour. At Glowwis Aesthetic & Medical Clinic, every Liquid PDO Thread Lift is performed by Dr Sam Pradeep — Medical Director, MOH-certified aesthetic physician, and Ultherapy Prime SPT-certified provider with over a decade of clinical experience in aesthetic medicine.

Unlike traditional thread lifts that insert solid threads beneath the skin, the Liquid PDO Thread Lift uses polydioxanone (PDO) — a biocompatible, biodegradable PDO collagen biostimulator with more than 30 years of established use in surgical sutures — delivered in a liquid, injectable form. The treatment stimulates the body’s own collagen-producing processes over time, supporting improvements in skin texture and firmness from within the dermis.

At Glowwis, no treatment protocol is one-size-fits-all. Dr Sam conducts a thorough clinical assessment of each patient’s skin condition, concerns, and anatomy before recommending a personalised plan. Results vary between individuals and are discussed openly during consultation.

Dr. Sam Pradeep
Glowwis Aesthetic & Medical Clinic
Medical Director
Book an Appointment

QUALIFIED
EXPERTS

CUSTOMISED
TREATMENTS

RELIABLE
& SAFE

PROVEN
RESULTS

Dr. Sam PDO12 (1)

What Is a Liquid PDO Thread Lift?

A Liquid PDO Thread Lift — also referred to as a liquid thread lift, PDO collagen biostimulator treatment, or non-surgical thread lift — is a minimally invasive injectable procedure using polydioxanone in liquid micro-particle form. Rather than mechanically lifting tissue through inserted threads, this treatment triggers the body’s wound-healing response: stimulating fibroblasts to produce new collagen and elastin fibres in a process known as neocollagenogenesis.

The PDO material used at Glowwis is approved by the KFDA (Korea Food and Drug Administration), which has independently evaluated the formulation’s biocompatibility and safety profile. PDO is gradually metabolised and eliminated by the body, leaving no permanent residue. PDO’s use in surgical sutures spans more than 30 years of documented clinical application.

This positions the Liquid PDO Thread Lift as a 4th-generation collagen biostimulatory treatment — distinct from dermal fillers (which add volume through material deposition) and from traditional thread lifts (which provide mechanical support through physical thread insertion).

How Does a Liquid PDO Thread Lift Work?

The procedure involves precise injection of a PDO solution — containing approximately 1,400 ultra-fine PDO micro-particles per ampoule — into the targeted layers of the dermis using a fine micro-cannula. The micro-cannula technique reduces trauma to surrounding tissue compared with standard needles and allows for more even distribution of the material across the treatment area. Once administered, the PDO micro-particles initiate neocollagenogenesis:

Collagen stimulation

PDO micro-particles stimulate fibroblasts — the skin’s collagen-producing cells — to generate new collagen and elastin fibres. Studies confirm that PDO threads promote collagen synthesis and vascularisation in the treated area.

Structural scaffolding

As the PDO solution integrates within the tissue, it provides a temporary structural framework that supports the skin’s internal architecture.

Natural absorption

Over the following weeks and months, the PDO material is gradually metabolised and eliminated by the body. The newly generated collagen fibres remain, contributing to observable improvements in skin firmness and texture.

PDO100 vs PDO200 — What Is the Difference?

 

Two particle sizes of PDO are used in clinical practice. PDO100 micro-particles are smaller in size and injected superficially within the skin dermis, making them most appropriate for delicate areas such as the under-eye region and fine lines. PDO200 micro-particles are larger and can be injected deeper into the subcutaneous tissue, providing more structural support in areas such as the jawline and cheeks. Dr Sam will advise on the most appropriate formulation for your treatment areas during consultation.

What Can Be Treated with a Liquid PDO Thread Lift?

Liquid PDO injections may be applied to a range of facial and body areas to address signs of ageing. The specific treatment plan — including the areas addressed and the volume of PDO used — is determined individually by Dr Sam following a thorough clinical assessment.

Face

The face is the most commonly treated area. Target regions include:

  • Cheeks and mid-face: to address volume loss and improve facial contour
  • Jawline: to refine definition and address mild skin laxity
  • Nasolabial folds (smile lines): to soften the appearance of these lines
  • Forehead: to improve texture and skin firmness
  • Brow area: as part of an overall lifting and contouring assessment
  • Crow’s feet and perioral fine lines: PDO100 micro-particles may be used to address fine lines around the eyes and mouth
Under-Eyes and Tear Troughs

The under-eye area is a technically delicate region. PDO100 micro-particles may be used to address skin laxity, improve skin texture, and reduce the hollowed appearance associated with tear trough volume loss. Dark circles related to volume loss and skin translucency may also be addressed through the collagen-stimulating effect of this treatment. Dr Sam will assess suitability carefully during your consultation.

Neck and Submental Area

The neck and submental (under-chin) area commonly show early signs of ageing including crepey skin texture, neck lines, and reduced firmness. Liquid PDO treatment in this region stimulates collagen to improve skin quality and texture over time.

Hands

The hands are an often-overlooked treatment area. Liquid PDO thread lift may be considered for patients experiencing volume loss or skin laxity in the dorsum of the hands — addressing wrinkles and the bony appearance that commonly accompanies age-related volume change.

Potential Benefits of Liquid PDO Thread Lift

Benefits are individual and depend on each patient’s skin condition, age, and the areas treated. Results vary between individuals. Dr Sam will discuss realistic expectations with you during your consultation. Potential benefits that may be observed over time include:

Improvements in skin firmness and elasticity as new collagen is produced

A more defined facial contour, particularly along the jawline and cheeks

Reduced appearance of fine lines, wrinkles, and skin crepiness in treated areas

Improved skin texture, hydration, and overall skin quality

Reduction in the hollowed appearance of the under-eye and tear trough region

Improved facial contour along the cheeks and jawline, which may contribute to a more defined facial profile

Minimal downtime — most patients resume normal activities shortly after treatment

No surgical incisions, general anaesthesia, or prolonged recovery period

Results develop gradually as the collagen response matures. Visible improvements typically develop over 2–3 months following treatment. The onset, extent, and duration of improvements vary between individuals.

Am I a Suitable Candidate for Liquid PDO Thread Lift?

Suitability is determined through a face-to-face clinical assessment with Dr Sam. The following provides general guidance — it is not a substitute for a professional consultation, and treatment is not appropriate for everyone.

Patients Who May Be Considered

  • Adults presenting with one or more of the following concerns may be assessed for this treatment:
  • Mild to moderate skin laxity affecting the face, neck, or hands
  • Fine lines, wrinkles, or skin crepiness that have not responded adequately to topical skincare
  • Volume loss in the cheeks, under-eye area, or mid-face
  • Dark circles related to volume loss and skin quality changes under the eyes
  • A preference for gradual, natural-looking collagen stimulation without surgery
  • Patients who have had dermal fillers and wish to explore a complementary biostimulatory approach
  • Patients in their 30s–60s noticing early-to-moderate signs of facial ageing

Treatment May Not Be Appropriate For Patients Who

  • Are pregnant or breastfeeding
  • Have active skin infection or inflammation in the treatment area
  • Have a known allergy or sensitivity to PDO or local anaesthetic agents
  • Have certain autoimmune conditions or take medications that may affect healing or collagen production

 

Dr Sam will review your full medical history during consultation and advise on whether this treatment is appropriate for you. No treatment proceeds without a consultation first.

Liquid PDO Thread Lift vs Traditional Thread Lift vs HIFU — What Is the Difference?

The following comparison is provided for general information only. It is not intended to suggest that any treatment is superior to another — suitability depends entirely on individual clinical assessment by Dr Sam.

Feature Liquid PDO Thread Lift Traditional Thread Lift HIFU / Ultherapy Prime
Mechanism Injectable PDO micro-particles stimulate collagen production within the dermis Solid PDO threads inserted under skin to physically lift tissue Microfocused ultrasound energy stimulates collagen at SMAS and dermal layers
Depth of action Intradermal — within the skin Subdermal — beneath the skin Deep tissue — SMAS and dermal layers
Downtime Minimal — mild swelling or redness may occur Moderate — bruising and swelling more common Minimal — some tenderness may occur
Onset of results Gradual — 2–3 months More immediate mechanical lift Gradual — 2–3 months
Procedure time ~30–45 minutes 45–90 minutes ~60–90 minutes
Suitable for Skin laxity, texture, fine lines, volume loss More pronounced laxity, jowling Deep structural laxity at SMAS layer
PDO particle specificity PDO100 (superficial) and PDO200 (deeper) available N/A — solid barbed or smooth threads N/A — energy-based, no material introduced
Material regulatory status KFDA-approved in liquid form PDO threads (various suppliers) FDA-cleared device (Ultherapy)
Can be combined with? Yes — Ultherapy Prime, dermal fillers, BTX Yes — with other injectables Yes — Liquid PDO, fillers, BTX

Dr Sam will advise on the most appropriate treatment — or staged combination — following your clinical assessment.

Maximise Your Results with Ultherapy Prime

Liquid PDO Thread Lift works by stimulating your body’s own collagen production from within the skin — improving firmness, elasticity, and texture at the intradermal level. For patients who wish to take their results further, pairing Liquid PDO Thread Lift with Ultherapy Prime creates a deeper, more comprehensive lifting outcome that addresses the face across multiple tissue layers.

Why Ultherapy Prime Complements Liquid PDO Thread Lift

Liquid PDO Thread Lift improves the skin from within the dermis. Ultherapy Prime works at a deeper level — targeting the superficial muscular aponeurotic system (SMAS), the same deep structural layer addressed during a surgical facelift. By stimulating long-term collagen remodelling at this foundational layer, Ultherapy Prime creates a structural support beneath the skin that allows the surface improvements from Liquid PDO Thread Lift to sit more naturally, look more refined, and be better sustained over time.

In simple terms: Ultherapy Prime lifts the foundation. Liquid PDO Thread Lift refines the surface above it.

What the Combination May Support
  • Deep SMAS-level structural lifting via Ultherapy Prime — creating foundational support that underpins surface results
  • Intradermal collagen stimulation and skin quality improvement via Liquid PDO Thread Lift
  • More natural-looking surface results, supported by a structurally lifted foundation beneath
  • Enhanced jawline definition and a more sculpted facial contour
  • Dual-layer collagen remodelling with minimal downtime associated with both treatments
About Ultherapy Prime at Glowwis

Ultherapy Prime is an FDA-cleared, non-invasive lifting treatment using microfocused ultrasound energy to stimulate collagen remodelling at the SMAS and dermal layers. Unlike generic HIFU devices, Ultherapy Prime incorporates real-time ultrasound imaging directly into the treatment handpiece — allowing Dr Sam to visualise individual skin layers and tissue depth before delivering any energy.

At Glowwis, every Ultherapy Prime treatment is guided by the SPT (See, Plan, Treat) protocol — a structured, imaging-led approach that personalises the treatment map to your exact anatomy. Dr Sam is a certified SPT provider with over 10 years of clinical experience in aesthetic medicine.

The Treatment Process at Glowwis — Step by Step

Step 1: Consultation with Dr Sam

Every treatment at Glowwis begins with a face-to-face consultation. Dr Sam reviews your medical history, assesses your skin condition, and discusses your concerns and expectations in detail. Suitability is determined and a personalised treatment plan is developed. No treatment proceeds without a consultation first.

Step 2: Treatment Preparation

A topical numbing cream is applied to the treatment area prior to the procedure to support patient comfort. The injection sites are cleaned and prepared according to clinical protocol.

Step 3: Liquid PDO Injection

Dr Sam administers the PDO solution using a fine micro-cannula, allowing precise, even distribution of the material across the treatment area. The procedure typically takes 30 to 45 minutes, depending on the number of areas treated and the volume of PDO required.

Step 4: Post-Treatment Assessment and Aftercare Guidance

Following the procedure, Dr Sam assesses the treatment area and provides personalised aftercare instructions. Common post-treatment effects — mild swelling, redness, or temporary tenderness — are discussed along with the expected timeline for visible improvement.

Recovery and Post-Treatment Care

The Liquid PDO Thread Lift is associated with minimal downtime for most patients. The following guidance is general — Dr Sam will provide specific aftercare advice tailored to your treatment.

  • Mild swelling or redness at injection sites is common and typically resolves within a few days
  • Bruising may occasionally occur, particularly in more vascular areas such as the under-eye region
  • Avoid strenuous exercise, extreme heat (saunas, steam rooms), and alcohol for 24–48 hours post-treatment
  • Avoid facial massage or strong pressure over treated areas for approximately one week
  • Continue with a gentle skincare routine — avoid active exfoliants (AHA/BHA/retinoids) for the first week post-treatment
  • Apply broad-spectrum SPF 30+ daily during the recovery period and beyond

Visible improvements develop gradually as the collagen response matures. Results typically develop over 2–3 months following treatment. Some patients notice early improvements in skin texture and firmness within the first few weeks. Results vary between individuals.

start today

Find Out Whether Liquid PDO Thread Lift Is Right for You

Speak to Dr Sam Pradeep for a personalised clinical assessment at Glowwis Aesthetic & Medical Clinic.

BOOK A CONSULTATION
Dr. Sam PDO9 - Edited

Cost of Liquid PDO Thread Lift in Singapore

The cost of Liquid PDO Thread Lift in Singapore typically ranges from SGD 500 to SGD 1,500, depending on the treatment areas and the complexity of the individual case. The cost for multiple areas or a combination treatment plan with Ultherapy Prime will differ — Dr Sam will provide a detailed and transparent quote following your clinical assessment.

For a personalised cost estimate, contact Glowwis via WhatsApp at +65 6908 9705 or email [email protected]. All pricing is presented as net pricing with no hidden charges.

Meet Our Doctor

About Dr Sam Pradeep

Glowwis Aesthetic & Medical Clinic, Medical Director

Dr Sam Pradeep is the Founder and Medical Director of Glowwis Aesthetic & Medical Clinic. He holds a Bachelor of Medicine and Bachelor of Surgery (MBBS) and is registered with the Singapore Medical Council. Dr Sam has over 10 years of clinical experience in aesthetic medicine, with specialised training in Anaesthesia and chronic pain management — a background that directly informs his approach to safe, comfortable aesthetic procedures.

Dr Sam is a certified Ultherapy Prime SPT (See, Plan, Treat) provider and administers all Liquid PDO Thread Lift treatments at Glowwis personally. His approach is doctor-led and assessment-first: every treatment protocol is built around the individual patient’s anatomy, skin condition, and goals.

Read Full Bio

Frequently Asked Questions About Liquid PDO Thread Lift in Singapore

What is a Liquid PDO Thread Lift?

A Liquid PDO Thread Lift is a non-surgical injectable treatment using polydioxanone (PDO) in liquid form. Unlike traditional thread lifts that insert solid threads to mechanically lift tissue, the PDO material is delivered via a micro-cannula as an injectable solution, where it stimulates natural collagen and elastin production over time through a process called neocollagenogenesis. All treatments at Glowwis are performed by Dr Sam Pradeep following a face-to-face consultation.

How is a Liquid PDO Thread Lift different from a traditional thread lift?

Traditional thread lifts use solid PDO threads inserted with a needle to physically lift and reposition tissue. The Liquid PDO Thread Lift delivers PDO in injectable liquid form via a micro-cannula — without inserting solid threads. Both treatments stimulate collagen through the body’s wound-healing response, but through different mechanisms. Dr Sam will advise on the most appropriate approach for your concerns following assessment.

How is Liquid PDO Thread Lift different from HIFU or Ultherapy Prime?

Liquid PDO Thread Lift uses an injectable PDO collagen biostimulator to work within the dermis (intradermal level). HIFU — including Ultherapy Prime — uses microfocused ultrasound energy to target the SMAS, a deeper structural layer beneath the skin. The two treatments work at different tissue depths and may be combined in some cases. Dr Sam will advise on the right approach or combination following your clinical assessment.

Who is a suitable candidate for Liquid PDO Thread Lift?

Adults experiencing mild to moderate skin laxity, fine lines, volume changes, or skin texture concerns in the face, neck, or hands may be considered for this treatment. Treatment is assessed individually by Dr Sam. It is not appropriate during pregnancy or breastfeeding, or in the presence of active skin infection or certain autoimmune conditions. A face-to-face consultation is required to determine suitability.

What areas can be treated with Liquid PDO Thread Lift?

Treatment may be applied to the face (cheeks, jawline, nasolabial folds, forehead, brow area, crow’s feet, perioral lines), the under-eye and tear trough region, the neck and submental area, and the hands. Specific areas treated and the volume of PDO used are determined by Dr Sam following a detailed clinical assessment.

Is there any downtime after a Liquid PDO Thread Lift?

Downtime is generally minimal. Mild swelling, redness, or temporary tenderness at the injection sites is common and typically resolves within a few days. Bruising may occasionally occur. Most patients resume their normal routine shortly after the procedure. Dr Sam will provide specific aftercare guidance tailored to your treatment.

How many sessions of Liquid PDO Thread Lift are needed?

The number of sessions depends on the degree of skin laxity, the areas treated, and your aesthetic goals. Some patients may benefit from a single session, whilst others with more significant laxity may require a course of treatments. Dr Sam will advise on a personalised plan following consultation. Results develop gradually and are not immediate.

How much does a Liquid PDO Thread Lift cost in Singapore?

The cost typically ranges from SGD 500 to SGD 1,500, depending on the areas treated and the number of sessions recommended. For a personalised quote, contact Glowwis via WhatsApp at +65 6908 9705 or email [email protected] to arrange a consultation with Dr Sam.

Is a Liquid PDO Thread Lift safe?

PDO (polydioxanone) is a biocompatible, biodegradable material used in surgical sutures for over 30 years. The PDO formulation at Glowwis is approved by the KFDA. When performed by a doctor using a micro-cannula technique, the procedure is designed to minimise tissue trauma. As with any medical procedure, potential risks and side effects exist — these are discussed openly by Dr Sam during consultation.

Can Liquid PDO Thread Lift be combined with other treatments?

In some cases, Liquid PDO Thread Lift may be considered alongside Ultherapy Prime, dermal fillers, or BTX injections to address multiple concerns at different tissue depths. Whether a combination approach is appropriate depends on your individual clinical assessment by Dr Sam. Treatment sequencing and timing are important — Dr Sam will advise accordingly.

How long do Liquid PDO Thread Lift results last?

Duration of results varies between individuals and depends on factors including age, skin condition, lifestyle, and the areas treated. Results are not permanent. Dr Sam will advise on the expected timeframe for your individual assessment and discuss maintenance options during your consultation.

What is the difference between PDO100 and PDO200 particles?

PDO100 refers to smaller PDO micro-particles injected superficially within the dermis — most suitable for fine lines and delicate areas such as the under-eye region. PDO200 refers to larger particles that can be injected deeper into the subcutaneous tissue, providing more support in areas such as the cheeks and jawline. Dr Sam will select the appropriate formulation based on your individual anatomy and treatment areas.

Why Choose Glowwis for Liquid PDO Thread Lift?

Differentiator What This Means for You
Doctor-Led Treatment by Dr Sam Pradeep Every Liquid PDO Thread Lift at Glowwis is performed by Dr Sam Pradeep personally — Medical Director, MOH-certified physician, MBBS, and Ultherapy Prime SPT-certified provider.
Personalised Assessment First No treatment is recommended without a thorough face-to-face clinical assessment. Dr Sam evaluates your skin, medical history, and goals before proposing any protocol.
KFDA-Approved PDO Material The PDO formulation used at Glowwis is approved by the KFDA (Korea Food and Drug Administration) for its biocompatibility and safety profile.
Micro-Cannula Technique A fine micro-cannula is used for injection — minimising trauma to surrounding tissue and allowing precise, even distribution of the PDO material across the treatment area.
PDO100 and PDO200 Particle Selection Dr Sam selects the appropriate PDO particle size for each treatment area — finer particles for delicate areas such as the under-eyes, larger particles for structural areas such as the cheeks and jawline.
Combination Treatment Planning Where appropriate, Dr Sam plans a staged combination approach — such as Liquid PDO Thread Lift with Ultherapy Prime — to address different tissue depths for a more comprehensive outcome.
Transparent Expectation Setting Dr Sam discusses realistic outcomes, potential side effects, and the expected development of results openly — before any treatment proceeds. Results vary between individuals.
MOH-Licensed Aesthetic Clinic Glowwis Aesthetic & Medical Clinic is licensed under the Ministry of Health Singapore. All clinical practice and content complies with MOH Advertisement Regulations 2019.
start today

Book a Consultation with Dr Sam Pradeep

To find out whether a Liquid PDO Thread Lift is appropriate for your concerns, book an in-person consultation at Glowwis Aesthetic & Medical Clinic. Dr Sam will conduct a thorough skin assessment and advise on the most suitable options for you.

Book A Consultation

talk to our team

Fill up the form and we will get back to you as soon as possible.






    For Faster Response, Call Us!
    +65‎ 6908‎ 9705

    Glowwis Aesthetic & Medical Clinic

    CAPITOL PIAZZA 13, Stamford Road
    
#B2 – 12/13, Singapore 178905
    +65‎ 6908‎ 9705
    [email protected]
    • Mon to Fri: 11am – 8pm
    • Sat: 11am – 4pm
    • Sunday & PH: Closed
    WHATSAPP US AT
    +6596403064