SEE
Before any energy is delivered, the device’s handpiece is used to visualise the tissue layers beneath your skin. The SMAS depth, tissue thickness, and structural anatomy specific to your face are all assessed and documented.
Ultherapy Prime is a U.S. FDA-cleared, non-invasive skin-tightening treatment that uses microfocused ultrasound energy to target the SMAS — the deep structural layer of the face.
At Glowwis Aesthetic & Medical Clinic in Singapore, every session is personally guided by Dr Sam Pradeep using the SPT (See, Plan, Treat) protocol, which incorporates real-time imaging to personalise each treatment to your individual anatomy.
Available at Capitol Piazza, Singapore.
Ultherapy Prime is a non-surgical, non-invasive skin-lifting treatment that uses microfocused ultrasound energy to address facial skin laxity. Cleared by the U.S. Food and Drug Administration (FDA), it is clinically distinct from generic high-intensity focused ultrasound (HIFU) devices in one meaningful way: your doctor can see your skin layers in real time before and during treatment.
Most energy-based devices deliver ultrasound energy without direct visualisation of the underlying tissue. Ultherapy Prime’s integrated imaging capability allows the treating physician to identify the exact depth and quality of tissue structures unique to your face — and then treat accordingly.
The energy is delivered to the superficial muscular aponeurotic system, or SMAS — the same deep structural layer that surgeons address during a surgical facelift. By stimulating this foundational layer, Ultherapy Prime aims to support gradual collagen remodelling from within, rather than addressing surface-level concerns alone.
In November 2025, Ultherapy Prime received additional FDA clearance for treatment of the arms and abdomen — an expansion that few clinics in Singapore currently offer.
| Feature | Original Ultherapy | Ultherapy Prime |
|---|---|---|
| Imaging Screen | Standard | 35% larger, higher resolution |
| Processing Speed | Standard | Faster dual-core processor |
| Comfort Profile | Moderate | Refined energy delivery for improved comfort |
| FDA-cleared Areas | Face, neck, décolletage | Also arms & abdomen (Nov 2025) |
| Treatment Protocol | Standard | SPT — See, Plan, Treat |
Ultherapy Prime follows the SPT (See, Plan, Treat) protocol — a structured clinical approach that uses real-time ultrasound imaging at every stage.
Before any energy is delivered, the device’s handpiece is used to visualise the tissue layers beneath your skin. The SMAS depth, tissue thickness, and structural anatomy specific to your face are all assessed and documented.
Based on what is seen, a personalised treatment map is established — determining which transducer depths to use, how many lines of energy to deliver, and which zones to prioritise for your individual anatomy and clinical goals.
Energy is then delivered systematically, guided by the imaging data gathered during the SEE and PLAN stages. This anatomy-guided approach aims to ensure that each pulse reaches the intended tissue layer.
Every Ultherapy Prime session at Glowwis is personally guided by Dr Sam, a certified SPT provider with over 10 years of clinical experience in aesthetic medicine. This advanced, personalised mapping is included as standard in every session, at no additional charge.
Ultherapy Prime delivers energy at three precise depths using interchangeable transducers:
Dr Sam will determine which combination of depths is appropriate based on your individual assessment.
When ultrasound energy is delivered at each targeted depth, it creates thermal coagulation points (TCPs) — small, precisely controlled zones of heat within the tissue. Your body recognises these and initiates its natural wound-healing response.
Over the weeks and months that follow, this stimulates neocollagenesis — the production of new collagen fibres within the treated area. Collagen is the structural protein responsible for skin firmness and support. As collagen production declines with age, skin gradually loses its structural integrity.
Collagen remodelling timeline:
Ultherapy Prime is suitable for addressing skin laxity across several areas of the face and body. Following the November 2025 FDA clearance, the treatable areas now include:
Candidacy for Ultherapy Prime is determined through a thorough in-person clinical assessment. No online resource can replace this evaluation.
Ultherapy Prime is generally considered for individuals who:
The treatment may not be suitable during pregnancy or breastfeeding, or for those with certain medical conditions affecting the skin — all of which will be reviewed during your consultation.
Please inform Dr Sam of any medications or existing medical conditions prior to treatment. If your concerns are primarily driven by volume loss rather than laxity, alternative or combined approaches may be more appropriate — and Dr Sam will advise accordingly.
Your journey begins with a detailed consultation and clinical skin assessment. Our doctor will:
On treatment day, the skin is thoroughly cleansed. A topical numbing cream is applied and left for approximately 20–30 minutes before the session begins.
Treatment duration: approximately 30–45 minutes for focused areas such as the brow; 60–90 minutes for full face, neck, and submentum.
Downtime:
Most patients leave the clinic and return to their normal routine immediately. Any gentle skin responses, such as light flushing or mild puffiness, are brief and easily managed.
Immediate responses (expected and transient):
Results timeline:
Aftercare guidance:
These three treatments are commonly compared, but they differ meaningfully in technology, depth, and clinical application. Understanding these distinctions supports a more informed conversation with Dr Sam.
| Feature | Ultherapy Prime | Generic HIFU | Thermage |
|---|---|---|---|
| Energy type | Microfocused ultrasound | High-intensity focused ultrasound | Radiofrequency (RF) |
| Real-time imaging | ✓ Yes — tissue visualised before treatment | ✗ No — treats without visualisation | ✗ No |
| Tissue depth | 1.5mm / 3.0mm / 4.5mm (SMAS) | Varies by device | Dermis to deep dermis |
| Primary mechanism | Collagen stimulation via TCP at SMAS and dermis | Collagen stimulation | Collagen stimulation via RF heat |
| Downtime | Minimal | Minimal | Minimal |
| Result longevity | Approximately 12–18 months (individual variation) | Varies | Approximately 12–24 months (individual variation) |
| FDA clearance | ✓ Yes — face, neck, décolletage, arms, abdomen | Device-dependent | ✓ Yes |
| Ideal use case | Structural laxity; SMAS-level lifting | Varies by device and protocol | Surface texture; skin tightening |
A key clinical distinction: Ultherapy Prime is the only device in this category with real-time visualisation of the tissue layers being treated. Generic HIFU devices deliver energy without the doctor being able to see the tissue depth, anatomy, or structural variations beneath the surface. This distinction matters for precision, safety, and treatment personalisation.
Thermage and Ultherapy Prime are sometimes used in a complementary role — Thermage addresses surface texture and tone, while Ultherapy Prime targets the deeper structural layer. Dr Sam will advise whether a combined approach is appropriate for your clinical presentation.
Ultherapy Prime pricing in Singapore varies based on the scope of your individual treatment plan. Factors that influence cost include:
Brow-only sessions differ in scope from full face and neck
A full face and upper neck protocol typically involves 800–1,100 lines, with the exact number tailored to your anatomy and degree of laxity
The specific 1.5mm, 3.0mm, or 4.5mm transducers selected for your plan
SPT-certified clinics using authentic Ultherapy Prime devices operate under protocols that differ from clinics using non-certified or generic devices
Aesthetic medicine treatments in Singapore are priced inclusive of the treating physician’s assessment and clinical judgement
In many cases, Ultherapy Prime can be part of a broader, staged treatment plan. Dr Sam will advise on appropriate combinations and timing based on your clinical presentation.
Ultherapy Prime addresses skin laxity at its structural foundation — stimulating collagen remodelling deep within the SMAS and dermal layers. For patients who also wish to improve skin texture, surface firmness, and overall skin quality, Liquid PDO Threadlift can be introduced as a complementary add-on to extend the results of Ultherapy Prime closer to the skin’s surface.
Liquid PDO Threadlift is a fourth-generation injectable treatment that uses PDO mono threads delivered in liquid form — rather than inserting traditional physical threads beneath the skin. Once introduced, the liquid disperses evenly within the skin to stimulate the body’s own collagen production from within the dermal layer, working to improve skin firmness, elasticity, and texture over time. The result is smoother, tighter skin with a more contoured appearance, achieved with minimal downtime.
Ultherapy Prime provides the deep structural lift — targeting the SMAS and deeper dermal layers via microfocused ultrasound energy delivered under real-time imaging guidance. Liquid PDO Threadlift acts as a surface booster — filling the gap at the intradermal level to refine skin texture and elasticity in the layer directly above where Ultherapy Prime works.
Together, the two treatments support a more complete lifting and rejuvenation outcome:
This pairing is particularly well suited to patients whose concerns include both structural laxity and a visible decline in skin quality — and for whom Ultherapy Prime alone addresses the foundational lift, but not the full picture of surface texture improvement.
Dr Sam will assess whether adding Liquid PDO Threadlift is appropriate for your individual presentation, and advise on the correct sequencing and timing to ensure both treatments are delivered safely and to their full clinical potential.
Ultherapy Prime addresses structural laxity at the SMAS and dermal levels. Dermal fillers restore volume in areas where fat pad descent or resorption has created hollowness or deflation. These two approaches may complement each other when both laxity and volume loss are contributing to visible facial changes. Timing is important — our doctor will advise on sequencing.
Skin boosters and bioremodelling agents such as Profhilo target skin hydration, elasticity, and superficial skin quality. When combined with Ultherapy Prime’s deeper structural lift, this pairing may address both the foundational layer and the quality of the skin above it. Dr Sam will advise on appropriate intervals between treatments.
As outlined in the comparison section, these two modalities operate at different tissue levels. Thermage’s radiofrequency energy addresses the dermis and surface texture, while Ultherapy Prime targets the SMAS and deeper dermal layers. A planned combination — with appropriate intervals — may address a broader range of concerns than either treatment alone.
Combining treatments requires careful planning to avoid overlapping recovery periods or delivering overlapping energy to the same tissue zone too close together. Always discuss any treatments you are considering — or have recently had — with the doctor before proceeding.
Every patient is important to me! The most delightful aspect of my profession is to see the satisfaction of my patients and the biggest earning in my career is the patients trust on me.
Dr. Sam has many years of experience in the aesthetic medicine and has worked with industry professionals for more than a decade.
After obtaining his Bachelor of Medicine and Bachelor of Surgery (MBBS), his experience in Anaesthesia, ICU management, Chronic pain management have laid a solid foundation in understanding & managing the pain during aesthetic procedures in a safe and effective manner.
Dr. Sam’s Passion and desire in aesthetic medicine made him to work hard in mastering skills & obtaining required certifications to become an aesthetic physician.
If you are noticing changes in your jawline definition, brow heaviness, or skin firmness and would like to understand your options, Dr Sam is available to assess your skin and provide an honest, personalised recommendation.
No commitment required. Your consultation begins with a clinical assessment — not a sales presentation.
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Most patients describe the sensation as brief warmth or a tingling feeling at the moment each pulse of energy is delivered. Because there is minimal downtime involved, you can comfortably plan your session around any day that suits you, with no recovery period to worry about afterwards. Dr Sam will discuss comfort management options during your consultation, which may include topical numbing cream or oral analgesics.
Many patients address their clinical goals with a single session. Whether additional sessions are appropriate depends on your individual response, the degree of laxity present, and the doctor’s assessment at follow-up. Maintenance sessions are sometimes recommended to help sustain outcomes over time as the ageing process continues.
Results vary among individuals. Many patients report improvements that are maintained for approximately 12–18 months, after which periodic maintenance may be considered. The rate at which your skin continues to age, your lifestyle, and your baseline skin quality all influence longevity.
Ultherapy Prime is the only microfocused ultrasound device with real-time tissue visualisation integrated into the treatment handpiece. This allows the doctor to see the exact depth and structure of your skin layers before delivering energy. Generic HIFU devices treat without this imaging capability. Ultherapy Prime is also the only ultrasound lifting device with U.S. FDA clearance for its specific indications. Device quality, protocols, and clinical training standards vary significantly among the generic HIFU machines available in Singapore.
Ultherapy Prime has a well-established comfort profile in the medical literature and is widely appreciated by patients when performed by a caring, experienced specialist using an authentic device. Any responses your skin may have are typically gentle and brief: a soft warmth or light flushing that tends to fade within a few hours, mild puffiness that usually settles within a day, and a subtle sensitivity that may linger for a couple of days. Occasional light bruising may appear and generally clears within one to two weeks. Some patients notice a gentle tingling or a temporary shift in sensation in the treated area, which naturally resolves on its own with time. In very rare instances, some may experience brief nerve sensitivity or minor surface-level skin changes — possibilities that are greatly minimised when treatment is guided by real-time imaging in the hands of a skilled specialist.
Collagen remodelling is a gradual biological process. Some patients begin to notice subtle changes in skin firmness and definition within the first few weeks. Many patients report more visible improvements at 2–3 months, with further refinement continuing up to 6 months post-treatment. Individual results and timelines vary.
Pricing depends on the treatment zones, number of energy lines, transducer selection, and doctor’s professional fee. Costs are determined following a clinical assessment. Please contact our clinic for a personalised consultation and cost discussion.
Ultherapy Prime delivers energy beneath the skin’s surface rather than at the surface, which means it does not pose the same pigmentation risks as certain laser or light-based treatments. It is generally considered suitable across a range of skin tones. Candidacy is assessed on an individual basis during your consultation.
SPT stands for See, Plan, Treat. It is a structured clinical protocol developed for Ultherapy Prime that uses the device’s integrated real-time imaging to assess tissue anatomy (SEE), document and personalise the treatment plan (PLAN), and deliver energy precisely to the identified target depths (TREAT). Glowwis is an SPT-certified clinic, with Dr Sam heading this protocol at no additional cost.
Yes. Skin laxity affects individuals regardless of gender, and Ultherapy Prime is suitable for men with mild to moderate laxity in the relevant areas. Male facial anatomy differs from female anatomy in tissue thickness and structure, which is accounted for during the real-time imaging and planning stage of the SPT protocol.